{"id":519,"date":"2020-10-09T14:40:30","date_gmt":"2020-10-09T14:40:30","guid":{"rendered":"http:\/\/nerb.team\/?page_id=519"},"modified":"2021-08-05T08:38:35","modified_gmt":"2021-08-05T08:38:35","slug":"luc-mallet","status":"publish","type":"page","link":"https:\/\/nerb.team\/index.php\/luc-mallet\/","title":{"rendered":"Luc Mallet"},"content":{"rendered":"\t\t
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Luc Mallet<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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MD, PHD, PU-PH, APHP

Date and place of birth :\n20th January 1967, Paris (XIV)<\/span>

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ORCID :\n0000-0001-8061-1167<\/span><\/span><\/p>\n\n

E-mail : <\/span>luc.mallet@inserm.fr<\/span><\/a><\/span> ; <\/span>luc.mallet@unige.ch<\/span><\/a><\/span> <\/span><\/span><\/p>\n\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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MD PhD, he was trained in Psychiatry and Neurosciences. He has been Professor Assistant in the University Department of Psychiatry in Paris 12 (Cr\u00e9teil) and Paris 6 (Piti\u00e9-Salp\u00eatri\u00e8re) and worked on functional imaging at the CEA. After his post-doctoral training in experimental psychology in a CNRS research unit, he was recruited at the Inserm in 2004 to study the behavioral aspects of the deep brain stimulation in human, and to develop innovative treatments in psychiatry. Since 2008, he leads the BEBG team in the Brain and Spine Institute (ICM), wherein the main focus of research is the identification of processes involved in the treatment of information by the basal ganglia and its links to psychopathology, as well as the development of innovative treatments for severe neuropsychiatric disorders that are resistant to medical therapy. In particular, he coordinates a series of translational research projects aimed at characterizing the pathophysiology of repeated pathological behaviors in humans, including obsessive-compulsive disorder (OCD). Since 2020, he started to develop a translational program research with Eric Burgui\u00e8re on psychedelics for the treatment of psychiatric disorders, with the use of LSD for the treatment of severe alcohol dependence and psilocybin for OCD.<\/p>

\u00a0<\/p>

Position: <\/em><\/strong>Professor of Psychiatry, D\u00e9partement M\u00e9dical-Universitaire de Psychiatrie et d\u2019Addictologie, APHP, UPEC, Cr\u00e9teil, France; Associate Professor, Psychiatric Department & Institute of Global Health, University of Geneva; ICM (Paris Brain Institute) researcher; Chief Editor of CQFPSY (Congr\u00e8s Fran\u00e7ais de Psychiatrie Newsletter)<\/p>

Education: <\/em><\/strong>Residency in Psychiatry, Paris 5 University, 1996; M.D., Paris 5 University, 1996 ; Neuroscience Post-graduate Diploma (DEA), Orsay CEA-DSV, Paris 6 University, 1993; PhD Thesis on functional imaging (2002, UPMC, CEA, France); Post-doctoral training in experimental psychology (2002-2004, CNRS, France)<\/p>

Awards, honors: <\/em><\/strong>French Academy of Sciences Philippe and Maria Halphen Great Prize in 2015; <\/em><\/strong>Marcel Dassault prize for the research in mental diseases, \u201cresearcher of the year\u201d 2013 ; <\/em><\/strong>STOC project (Stimulation of the subthalamic nuclei for the treatment of severe and resistant OCD, coordinated by L Mallet) distinguished in 2013: 20 years of the PHRC \u2013 20 projects selected, Health Ministry, France<\/p>

Boards, learned societies, memberships, expertise: <\/em><\/strong>General Secretary fo the Congr\u00e8s Fran\u00e7ais de Psychiatrie, Secretary of the French Brain Council, Steering Committee of the LABEX BIOPSY (Paris), Scientific Advisory Board Member of the ERA-Net NEURON (Network of European Funding for Neuroscience Research) 2015-2020, Director of the FondaMental Swiss Foundation (Geneva 2015-2021)<\/p>

Ongoing Grants: <\/strong>IRESP21 ADELY : Treatment of Alcohol DEpendence with LYsergic acid diethylamide: translational approach and clinical efficacy study (PI); ANR SAMENTA HYPSY\u00a0: HYperdirect pathway in PSYchiatry: Anatomo-functional characterization of the cortical-subthalamic pathway and its relevance for the treatment of OCD by deep-brain stimulation (Co-PI; no overlap); <\/strong>STUC – PHRC AOR11036: SCP pilot study of cocaine users with addiction and severe complications ( PI, no overlap); <\/strong>Fondation Priv\u00e9e des HUG \u2013 CONFIRM\u00a0: OptoDBS: deep brain stimulation treatments for obsessive-compulsive disorders based on optogenetic circuit explorations. (Co-PI, no overlap); <\/strong>Fondation pour la Recherche Medicale – TORPIDO: Towards identification of response predictors in deep\u00adbrain stimulation of subthalamic nucleus for obsessive compulsive disorder. (PI, no overlap)<\/p>

Student supervision: <\/strong>8 PhDs, 2 MDs; one ongoing PhD.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Publications:<\/strong><\/p>

Lamothe, H., Tamouza, R., Hartmann, A., & Mallet, L.<\/u> (2021). Immunity and Gilles de la Tourette syndrome: A systematic review and meta\u2010analysis of evidence for immune implications in Tourette syndrome.\u00a0European Journal of Neurology<\/em>.<\/p>

Arumugham, S. S., Srinivas, D., Narayanaswamy, J. C., Jaisoorya, T. S., Kashyap, H., Domenech, P., Palfi, S., Mallet, L.,<\/u> Venkatasubramanian, G., & Reddy, Y. J. (2021). Identification of biomarkers that predict response to subthalamic nucleus deep brain stimulation in resistant obsessive\u2013compulsive disorder: protocol for an open-label follow-up study. BMJ open<\/strong>, 11(6), e047492.<\/p>

Benzina, N., N\u2019diaye, K., Pelissolo, A., Mallet, L.,<\/u> & Burgui\u00e8re, E. (2021). A cross-species assessment of behavioral flexibility in compulsive disorders.\u00a0Communications Biology,<\/strong>\u00a04<\/em>(1), 1-12.<\/p>

Lamothe, H., Schreiweis, C., Lavielle, O., Mallet, L.,<\/u> & Burgui\u00e8re, E. (2021). Not only compulsivity: The SAPAP3-KO mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviors.\u00a0bioRxiv<\/strong>, 2020-01.<\/em><\/p>

Yrondi, A., Vaiva, G., Walter, M., Amato, T. D., Bellivier, F., Bennabi, D., … & Horn, M. (2021). Childhood Trauma increases suicidal behaviour in a treatment-resistant depression population: a FACE-DR report.\u00a0Journal of psychiatric research<\/strong>,\u00a0135<\/em>, 20-27. IF: 3.7<\/strong><\/p>

Baptista, A., Maheu, M., Mallet, L.,<\/u> & N’Diaye, K. (2020). <\/em>Joint contribution of metacognition and self-beliefs to uncertainty-guided checking behavior. Psyarxiv,<\/strong> 2020<\/em><\/p>

Welter ML, Flores Alves Dos Santos J, Clair AH, Lau B, Mamadou Diallo H, Fernandez-Vidal S, Belaid H, Pelissolo A, Domenech P, Karachi C, Mallet L.<\/u> Deep brain stimulation of the subthalamic, accumbens or caudate nuclei for patients with severe obsessive compulsive disorder: a randomized cross-over controlled study, Biological Psychiatry<\/strong>, https:\/\/doi.org\/10.1016\/j.biopsych.2020.07.013<\/p>

Buot A., Karachi C., Lau B., Belaid H., Fernandez-Vidal S., Welter M.-L. & Mallet L.,<\/u> Emotions modulate subthalamic nucleus activity: new evidence in obsessive-compulsive disorder and Parkinson disease patients, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging<\/strong> (2020), doi: https:\/\/doi.org\/10.1016\/j.bpsc.2020.08.002.<\/p>

Alves B, Mauvieux B, Besnard S, Lemarchand B, Mallet L,<\/u> Jouffroy R, E\u0301tude de la cine\u0301tique per-effort des parame\u0300tres des gaz du sang veineux au cours d\u2019un ultra-trail, Science &Sports<\/strong> (2020) 35, 58-60.<\/p>

Lamothe, H., Schreiweis, C., Mallet, L<\/u>., & Burguiere, E. (2020). The Sapap3-knockout mouse model manifests a spectrum of repetitive behaviours.\u00a0bioRxiv<\/em>.<\/p>

Oliveira, J., Maia, A., Lajnef, M., Mallet, L.,<\/u> Tamouza, R., Leboyer, M., & Oliveira\u2010Maia, A. J. (2020). Opportunities and challenges in meta\u2010analyses of oxidative and nitrosative stress markers in neuropsychiatric disorders.\u00a0Acta Psychiatrica Scandinavica,<\/strong>\u00a0141<\/em>(1), 89-90.<\/p>

Senova, S., Clair, A. H., Palfi, S., Yelnik, J., Domenech, P., & Mallet, L.<\/u> (2019). Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder: Towards an Individualized Approach.\u00a0Frontiers in Psychiatry<\/strong>,<\/strong>\u00a010<\/em>.<\/p>

Senova, S., Rabu, C., Beaumont, S., Michel, V., Palfi, S., Mallet, L.,<\/u> & Domenech, P. (2019). Stimulation du nerf vague dans le traitement de la d\u00e9pression.\u00a0La Presse M\u00e9dicale,<\/strong>\u00a048<\/em>(12), 1507-1519.<\/p>

Benzina, N., N\u2019Diaye, K., Pelissolo, A., Mallet, L.,<\/u> & Burgui\u00e8re, E. (2019). A cross-species assessment of behavioral flexibility in compulsive disorders.\u00a0bioRxiv<\/em>, 542100.<\/p>

Benzina, N, Morgi\u00e8ve M, Euvrard M, Flores Alves Dos Santos J, Pelissolo A, Mallet L.<\/u> \u00a0(2019). Personalised 360 video exposure therapy for the treatment of obsessive-compulsive disorder: a proof-of-concept study. psyRxiv<\/em><\/p>

Senova, S., Mallet, L.,<\/u> Gurruchaga, J. M., Rabu, C., Derosin, M., Yelnik, J., … & Domenech, P. Severe Obsessive-Compulsive Disorder Secondary to Neurodegeneration With Brain Iron Accumulation: Complete Remission After Subthalamic Nuclei Deep Brain Stimulation. Biological Psychiatry. <\/strong>2019<\/p>

Jouffroy, R., Alves, B., Mauvieux, B., Mallet, L., <\/u>Beaudeux, J. L., & Cottart, C. H. (2019, September). NSE & S100B protein blood level assessment during a long-distance trail race. In\u00a0Annales de biologie clinique<\/strong>\u00a0(Vol. 77, No. 5, pp. 532-536).<\/p>

Morgi\u00e8ve, M., N\u2019diaye, K., Nguyen-Khac, A., Mallet, L., <\/u>& Briffault, X. (2019). Crazy\u2019App: A web survey on representations and attitudes toward mental disorders using video testimonies.\u00a0L’Enc\u00e9phale,<\/strong>\u00a045<\/em>(4), 290-296.<\/p>

Lamothe H, Baleyte J-M, Mallet L<\/u>, Pelissolo A \u2018Trichotillomania is more related to Tourette disorder than to obsessive compulsive disorder\u2019, Brazilian Journal of Psychiatry<\/strong>, 2019<\/p>

Mallet, L<\/u>., Du Montcel, S. T., Clair, A.-H., Arbus, C., Bardinet, E., Baup, N., Chabard\u00e8s, S., Ch\u00e9reau, I., Czernecki, V., Fontaine, D., Harika-Germaneau, G., Haynes, W. I., Houeto, J.-L., Jaafari, N., Krack, P., Millet, B., Navarro, S., Polosan, M., Pelissolo, A. and Welter, M.-L. (2019) \u2018Long-term effects of subthalamic stimulation in Obsessive-Compulsive Disorder: Follow-up of a randomized controlled trial\u2019, Brain Stimulation<\/strong>, 12<\/em>(4), 1080-1082. doi: 10.1016\/j.brs.2019.04.004.<\/p>

Maia, A., Oliveira, J., Lajnef, M., Mallet, L.,<\/u> Tamouza, R., Leboyer, M. and Oliveira\u2010Maia, A. J. (2019) \u2018Oxidative and Nitrosative Stress Markers in Obsessive\u2010Compulsive Disorder: A Systematic Review and Meta\u2010Analysis\u2019, Acta Psychiatrica Scandinavica,<\/strong> pp. 1\u201314. doi: 10.1111\/acps.13026.<\/p>

Welter, M.-L., Houeto, J.-L., Worbe, Y., Diallo, M. H., Hartmann, A., Tezenas du Montcel, S., Ansquer, S., Thobois, S., Fontaine, D., Rouaud, T., Cuny, E., Karachi, C. and Mallet, L<\/u>. (2019) \u2018Long-term effects of anterior pallidal deep brain stimulation for tourette\u2019s syndrome\u2019, Movement Disorders,<\/strong> (January), pp. 2018\u20132019. doi: 10.1002\/mds.27645.<\/p>

Lamothe H, Baleyte J-M, Smith P, Pelissolo A, Mallet L<\/u>. Individualized Immunological Data for Precise Classification of OCD Patients. Brain Sci<\/strong>. 2018;8(8):149.<\/p>

Trenado C, Boschheidgen M, Ru\u0308benach J, N\u2019Diaye K, Schnitzler A, Mallet L<\/u> and Wojtecki L (2018) Assessment of Metacognition and Reversal Learning in Parkinson\u2019s Disease: Preliminary Results. Front. Hum. Neurosci<\/strong>. 12:343. doi: 10.3389\/fnhum.2018.0034<\/p>

Clair AH, Haynes W and Mallet L<\/u>. Recent advances in deep brain stimulation in psychiatric disorders [version 1; referees: 2 approved].\u00a0F1000Research\u00a02018<\/strong>,\u00a07(F1000 Faculty Rev):699 (doi:\u00a010.12688\/f1000research.14187.1<\/a>)<\/p>

Haynes WI, Clair AH, Fernadez-Vidal S, Gholipour, B, Morgi\u00e8ve M, Mallet L,<\/u> Altered anatomical connections of associative and limbic cortico-basal-ganglia circuits in obsessive-compulsive disorder, European Psychiatry<\/strong>, 2018;51:1\u20138.<\/p>

  1. Martinez-Ramirez, J. Jimenez-Shahed, J. F. Leckman, M. Porta, D. Servello, F.-G. Meng, J. Kuhn, D. Huys, J. C. Baldermann, T. Foltynie, M. I. Hariz, E. M. Joyce, L. Zrinzo, Z. Kefalopoulou, P. Silburn, T. Coyne, A. Y. Mogilner, M. H. Pourfar, S. M. Khandhar, M. Auyeung, J. L. Ostrem, V. Visser-Vandewalle, M.-L. Welter, L. Mallet<\/u>, C. Karachi, J. L. Houeto, B. T. Klassen, L. Ackermans, T. Kaido, Y. Temel, R. E. Gross, H. C. Walker, A. M. Lozano, B. L. Walter, Z. Mari, W. S. Anderson, B. K. Changizi, E. Moro, S. E. Zauber, L. E. Schrock, J.-G. Zhang, W. Hu, K. Rizer, E. H. Monari, K. D. Foote, I. A. Malaty, W. Deeb, A. Gunduz, and M. S. Okun, \u201cEfficacy and Safety of Deep Brain Stimulation in Tourette Syndrome: The International Tourette Syndrome Deep Brain Stimulation Public Database and Registry,\u201d JAMA Neurol.,<\/strong> vol. 32607, pp. 1\u20137, 2018.<\/li><\/ol>

    Welter ML, Houeto JL,\u00a0 Thobois S, Bataille B, Guenot M, Worbe Y, Hartmann A, Czernecki V,\u00a0 Bardinet E, Yelnik J, Tezenas du Montcel S,\u00a0 Agid Y, Vidailhet M, Cornu P, Tanguy, A, Ansquer S, Jaafari, N, Poulet, E, Serra G, Burbaud, P, Cuny E, Aouizerate B, Pollak, P, Chabardes S, Polosan M, Borg M, Fontaine D, Giordana B, Raoul S, Rouaud T, Sauvaget A, Jalenques I, Karachi C, Mallet L.<\/u> Anterior pallidal deep brain stimulation for Tourette\u2019s syndrome: a double-blind randomised parallel controlled trial. Lancet Neurology,<\/strong> Published online June 20, 2017 http:\/\/dx.doi.org\/10.1016\/S1474-4422(17)30160-6<\/p>

    Yrondi, D. Bennabi, E. Haffen, M. Garnier, F. Bellivier, T. Bourgerol, V. Camus, T. D\u2019Amato, O. Doumy, F. Haesebaert, J. Holtzmann, C. Lan\u00e7on, P. Vignaud, F. Moliere, I. Nieto, R. M. M. Richieri, P. Domenech, C. Rabu, L. Mallet<\/u>, L. Yon, L. Schmitt, F. Stephan, G. Vaiva, M. Walter, P.-M. M. Llorca, P. Courtet, M. Leboyer, W. El-Hage, and B. Aouizerate, Significant Need for a French Network of Expert Centers Enabling a Better Characterization and Management of Treatment-Resistant Depression (Fondation FondaMental). Front Psychiatry.<\/strong> 2017;8(NOV):244.<\/p>

    Doukhan, R., Mallet, L.,<\/u> & Pelissolo, A. A case of bleach addiction associated with severe obsessive-compulsive disorder.\u00a0Revista Brasileira de Psiquiatria<\/strong>, 2017, \u00a039<\/em>(2), 187-188.<\/p>

    Flores Alves Dos Santos J, T\u00e9zenas du Montcel S, Gargiulo M, Behar C, Montel S, Hergueta T, Navarro S, Belaid H, Cloitre P, Karachi V, Mallet L<\/u>, Welter M-L, Tackling the psychosocial maladjustment in Parkinson\u2019s disease patients following subthalamic deep-brain stimulation: a randomised clinical trial. PLoS ONE<\/strong>, 12(4): e0174512. https:\/\/doi.org\/10.1371\/journal. pone.0174512<\/p>

    Benzina, N., Mallet, L<\/u>., Burgui\u00e8re, E., N’Diaye, K., & Pelissolo, A.. Cognitive Dysfunction in Obsessive-Compulsive Disorder. Current Psychiatry<\/strong> Reports<\/strong> 2016, 1\u201311. http:\/\/doi.org\/10.1007\/s11920-016-0720-3<\/p>

    Gasnier, M., Pelissolo, A., Bondolfi, G., Pelissolo, S., Tomba, M., Mallet, L<\/u>., & N\u2019diaye, K. Les interventions bas\u00e9es sur la pleine conscience dans le trouble obsessionnel compulsif: m\u00e9canismes d\u2019action et pr\u00e9sentation d\u2019une \u00e9tude pilote. L\u2019Enc\u00e9phale<\/strong> 2016. http:\/\/dx.doi.org\/10.1016\/j.encep.2016.10.004<\/p>

    Morgi\u00e8ve M., N\u2019Diaye K., Fernandez-Vidal S., Clair A.-H., & Mallet L<\/u>. Le trouble obsessionnel compulsif vu par ceux qui y sont confront\u00e9s: enqu\u00eate aupr\u00e8s de patients, de proches et de cliniciens. L\u2019Enc\u00e9phale<\/strong> 2016. http:\/\/dx.doi.org\/10.1016\/j.encep.2016.07.004<\/p>

    Morgi\u00e8ve M, N’Diaye K, Clair A.H., Pelissolo A, and Mallet L<\/u>, \u201c[Can the efficacy of behavioral and cognitive therapy for obsessive compulsive disorder be augmented by innovative computerized adjuvant?],\u201d L’Enc\u00e9phale<\/strong> 2016; 42: 402\u2013409<\/p>

    1. Deeb, P. J. Rossi, M. Porta, V. Visser-Vandewalle, D. Servello, P. Silburn, T. Coyne, J. F. Leckman, T. Foltynie, M. Hariz, E. M. Joyce, L. Zrinzo, Z. Kefalopoulou, M.-L. Welter, C. Karachi, L. Mallet<\/u>, J.-L. Houeto, J. Shahed-Jimenez, F.-G. Meng, B. T. Klassen, A. Y. Mogilner, M. H. Pourfar, J. Kuhn, L. Ackermans, T. Kaido, Y. Temel, R. E. Gross, H. C. Walker, A. M. Lozano, S. M. Khandhar, B. L. Walter, E. Walter, Z. Mari, B. K. Changizi, E. Moro, J. C. Baldermann, D. Huys, S. E. Zauber, L. E. Schrock, J.-G. Zhang, W. Hu, K. D. Foote, K. Rizer, J. W. Mink, D. W. Woods, A. Gunduz, and M. S. Okun, \u201cThe International Deep Brain Stimulation Registry and Database for Gilles de la Tourette Syndrome: How Does It Work?,\u201d Front. Neurosci. <\/strong>2016,<\/strong> vol. 10, p. 1068, Apr. 2016.<\/li><\/ol>

      Pelissolo A, Moukheiber A, Mallet L<\/u>: Obsessive-compulsive disorders and anxiety disorders: A comparison of personality and emotionality patterns\u00a0 Psychiatry Research<\/strong> 2015; 229:695\u2013701<\/p>

      Alonso P, Cuadras D, Gabri\u00ebls L, Denys D, Goodman W, Greenberg BD, Jim\u00e9nez-Ponce F, Kuhn J, Lenartz D, Mallet L<\/u>, Nuttin B, Real E, Segal\u00e0s C, Schuurman R, T\u00e9zenas du Montcel S, Menchon JM: Deep Brain Stimulation for Obsessive-Compulsive Disorder: A Meta-Analysis of Treatment Outcome and Predictors of Response. PLoS ONE<\/strong> 2015; 10:e0133591<\/p>

      Burgui\u00e8re E, Monteiro P, Mallet L<\/u>, Feng G, Graybiel AM: Striatal circuits, habits, and implications for obsessive-compulsive disorder. Current Opinion in Neurobiology <\/strong>2015; 30:59\u201365<\/p>

      Bally J, L\u00fcscher C, Berney A, Mallet L<\/u>, Pollak P, Santos J: [Deep brain stimulation: new targets and new indications]. Rev Med Suisse<\/strong> 2015; 11:977\u201380\u2013 982<\/p>

      Welter M-L, Schupbach M, Czernecki V, Karachi C, Fernandez-Vidal S, Golmard J-L, Serra G, Navarro S, Welaratne A, Hartmann A, Mesnage V, Pineau F, Cornu P, Pidoux B, Worbe Y, Zikos P, Grabli D, Galanaud D, Bonnet A-M, Belaid H, Dormont D, Vidailhet M, Mallet L<\/u>, Houeto J-L, Bardinet E, Yelnik J, Agid Y. Optimal target localisation for subthalamic stimulation in Parkinson\u2019s disease patients. Neurology<\/strong>, March 19, 2014\u2028DOI 10.1212\/WNL.0000000000000315.<\/p>

      Dervaux A, Falissard B, Grohens M, Limosin F, Mercuel A, Triantafyllou M, Vidon G, Mallet L<\/u>, Plaze M, Laqueille X, Bocher R. Psychiatry in 2030\u00a0? Presse M\u00e9dicale<\/strong>, \u00a02014 Jan 15. pii: S0755-4982(13)00871-3.<\/p>

      Morgi\u00e8ve M*, N\u2019Diaye*, Haynes WIA, Granger B, Clair A-H, Pelissolo A, Mallet L<\/u>. Dynamics of psychotherapy-related cerebral haemodynamic changes in Obsessive Compulsive Disorder using a personalised exposure task in fMRI. Psychol Med,<\/strong> 2013 Sep 4:1-13.<\/p>

      Flores Alves dos Santos J, Mallet L<\/u>. Synth\u00e8se\u00a0: Le Trouble Obsessionnel Compulsif. M\u00e9decine\/Sciences<\/strong>, 2013 Dec;29(12):1111-6<\/p>

      Flores Alves dos Santos J, Mallet L<\/u>. [OCD: when limbic systems start looping…]. Rev Prat<\/strong> 2013; 63: 643-646.<\/p>

      Burbaud P, Clair AH, Langbour N, Fernandez-Vidal S, Goillandeau M, Michelet T, Bardinet E, Ch\u00e9reau I, Durif F, Polosan M, Chabard\u00e8s S, Fontaine D, Magni\u00e9-Mauro MN, Houeto JL, Bataille B, Millet B, V\u00e9rin M, Baup N, Krebs MO, Cornu P, Pelissolo A, Arbus C, Simonetta-Moreau M, Yelnik J, Welter ML, Mallet L<\/u>. Neuronal activity correlated with checking behaviour in the subthalamic nucleus of OCD patients. Brain<\/strong>, 2013 Jan;136(Pt 1):304-17<\/p>

      Clair AH, N’Diaye K, Baroukh T, Pochon JB, Morgieve M, Hantouche E, Falissard B, Pelissolo A, Mallet L<\/u>. Excessive checking for non-anxiogenic stimuli in obsessive-compulsive disorder. Eur Psychiatry<\/strong> 2012. 10.1016\/j.eurpsy.2012.11.003<\/p>

      Buot A, Welter ML, Karachi C, Pochon JB, Bardinet E, Yelnik J, Mallet L<\/u>. Processing of emotional information in the human subthalamic nucleus. J Neurol Neurosurg Psychiatry<\/strong> 2012, 84, 1331+<\/p>

      Evans D, Mallet L<\/u>, Flahault A, Cothereau C, Velazquez S, Capron L, Lejoyeux M. The importance of both workplace and private life factors in psychological distress: a large cross-sectional survey of French railway company employees. Social psychiatry and psychiatric epidemiology<\/strong> 2012. 10.1007\/s00127-012-0605-7<\/p>

      Brun Y, Karachi C, Fernandez-Vidal S, Jodoin N, Grabli D, Bardinet E, Mallet L<\/u>, Agid Y, Yelnik J, Welter ML. Does unilateral basal ganglia activity functionally influence the contralateral side? What we can learn from STN stimulation in patients with Parkinson’s disease. J Neurophysiol<\/strong> 2012; 108: 1575-1583.<\/p>

      Haynes WI, Millet B, Mallet L<\/u>. [Obsessive-compulsive disorder, a new model of basal ganglia dysfunction? Elements from deep brain stimulation studies]. Rev Neurol (Paris)<\/strong> 2012; 168: 649-654.<\/p>

      Palminteri S, Clair AH, Mallet L<\/u>, Pessiglione M. Similar improvement of reward and punishment learning by serotonin reuptake inhibitors in obsessive-compulsive disorder. Biol Psychiatry<\/strong> 2012; 72: 244-250.<\/p>

      Baunez C, Yelnik J, Mallet L<\/u>. Six questions on the subthalamic nucleus: lessons from animal models and from stimulated patients. Neuroscience<\/strong> 2011; 198: 193-204.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 IF: 3,4\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 C<\/p>

      Vorspan F, Mallet L<\/u>, Corvol JC, Pelissolo A, Lepine JP. Treating addictions with deep brain stimulation is premature but well-controlled clinical trials should be performed. Addiction<\/strong> 2011; 106: 1535-1536; author reply 1537-1538.<\/p>

      Bourredjem A, Pelissolo A, Rotge JY, Jaafari N, Machefaux S, Quentin S, Bui E, Bruno N, Pochon JB, Polosan M, Baup N, Papetti F, Chereau I, Arbus C, Mallet L<\/u>, du Montcel ST. A video Clinical Global Impression (CGI) in obsessive compulsive disorder. Psychiatry Res<\/strong> 2011; 186: 117-122.<\/p>

      Welter ML, Burbaud P, Fernandez-Vidal S, Bardinet E, Coste J, Piallat B, Borg M, Besnard S, Sauleau P, Devaux B, Pidoux B, Chaynes P, Tezenas du Montcel S, Bastian A, Langbour N, Teillant A, Haynes W, Yelnik J, Karachi C, Mallet L<\/u>. Basal ganglia dysfunction in OCD: subthalamic neuronal activity correlates with symptoms severity and predicts high-frequency stimulation efficacy. Transl Psychiatry<\/strong> 2011; 1: e5.<\/p>

      Le Jeune F, Verin M, N’Diaye K, Drapier D, Leray E, Du Montcel ST, Baup N, Pelissolo A, Polosan M, Mallet L<\/u>, Yelnik J, Devaux B, Fontaine D, Chereau I, Bourguignon A, Peron J, Sauleau P, Raoul S, Garin E, Krebs MO, Jaafari N, Millet B. Decrease of prefrontal metabolism after subthalamic stimulation in obsessive-compulsive disorder: a positron emission tomography study. Biol Psychiatry<\/strong> 2010; 68: 1016-1022.<\/p>

      Worbe Y, Mallet L<\/u>, Golmard JL, Behar C, Durif F, Jalenques I, Damier P, Derkinderen P, Pollak P, Anheim M, Broussolle E, Xie J, Mesnage V, Mondon K, Viallet F, Jedynak P, Ben Djebara M, Schupbach M, Pelissolo A, Vidailhet M, Agid Y, Houeto JL, Hartmann A. Repetitive behaviours in patients with Gilles de la Tourette syndrome: tics, compulsions, or both? PLoS One<\/strong> 2010; 5: e12959.<\/p>

      Haynes WIA, Mallet L<\/u>. High-frequency stimulation of deep brain structures in obsessive-compulsive disorder: the search for a valid circuit. European Journal of Neuroscience<\/strong> 2010; 32: 1118-1127.<\/p>

      Aouizerate B, Cuny E, Bardinet E, Yelnik J, Martin-Guehl C, Rotge JY, Rougier A, Bioulac B, Tignol J, Mallet L<\/u>, Burbaud P, Guehl D. Distinct striatal targets in treating obsessive-compulsive disorder and major depression. J Neurosurg<\/strong> 2009; 111: 775-779.<\/p>

      Ribeiro MJ, Thobois S, Lohmann E, du Montcel ST, Lesage S, Pelissolo A, Dubois B, Mallet L<\/u>, Pollak P, Agid Y, Broussolle E, Brice A, Remy P. A Multitracer Dopaminergic PET Study of Young-Onset Parkinsonian Patients With and Without Parkin Gene Mutations. J Nucl Med<\/strong> 2009.<\/p>

      Lohmann E, Thobois S, Lesage S, Broussolle E, du Montcel ST, Ribeiro MJ, Remy P, Pelissolo A, Dubois B, Mallet L<\/u>, Pollak P, Agid Y, Brice A. A multidisciplinary study of patients with early-onset PD with and without parkin mutations. Neurology<\/strong> 2009; 72: 110-116.<\/p>

      Welter ML, Pelissolo A, Mallet L. Subthalamic Nucleus Stimulation in Severe Obsessive-Compulsive Disorder – Reply. N Engl J Med<\/strong> 2008; 360: 932-932.<\/p>

      Mallet L<\/u>, Polosan M, Jaafari N, Baup N, Welter ML, Fontaine D, du Montcel ST, Yelnik J, Chereau I, Arbus C, Raoul S, Aouizerate B, Damier P, Chabardes S, Czernecki V, Ardouin C, Krebs MO, Bardinet E, Chaynes P, Burbaud P, Cornu P, Derost P, Bougerol T, Bataille B, Mattei V, Dormont D, Devaux B, Verin M, Houeto JL, Pollak P, Benabid AL, Agid Y, Krack P, Millet B, Pelissolo A. Subthalamic nucleus stimulation in severe obsessive-compulsive disorder. N Engl J Med<\/strong> 2008; 359: 2121-2134.<\/p>

      Rotge JY, Clair AH, Jaafari N, Hantouche EG, Pelissolo A, Goillandeau M, Pochon JB, Guehl D, Bioulac B, Burbaud P, Tignol J, Mallet L<\/u>, Aouizerate B. A challenging task for assessment of checking behaviors in obsessive-compulsive disorder. Acta Psychiatr Scand<\/strong> 2008; 117: 465-473.<\/p>

      Welter ML*, Mallet L<\/u>*, Houeto JL, Karachi C, Czernecki V, Cornu P, Navarro S, Pidoux B, Dormont D, Bardinet E, Yelnik J, Damier P, Agid Y. Internal pallidal and thalamic stimulation in patients with Tourette syndrome. Arch Neurol<\/strong> 2008; 65: 952-957.<\/p>

      Montefiore D, Mallet L<\/u>, Levy R, Allilaire JF, Pelissolo A. [Pseudo-dementia conversion and post-traumatic stress disorder]. Encephale<\/strong> 2007; 33: 352-355.<\/p>

      Mallet L<\/u>, Schupbach M, N’Diaye K, Remy P, Bardinet E, Czernecki V, Welter ML, Pelissolo A, Ruberg M, Agid Y, Yelnik J. Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior. Proc Natl Acad Sci U S A<\/strong> 2007; 104: 10661-10666.<\/p>

      Schupbach WM, Maltete D, Houeto JL, du Montcel ST, Mallet L<\/u>, Welter ML, Gargiulo M, Behar C, Bonnet AM, Czernecki V, Pidoux B, Navarro S, Dormont D, Cornu P, Agid Y. Neurosurgery at an earlier stage of Parkinson disease: a randomized, controlled trial. Neurology<\/strong> 2007; 68: 267-271.<\/p>

      Schupbach MW, Welter ML, Bonnet AM, Elbaz A, Grossardt BR, Mesnage V, Houeto JL, Maltete D, Mallet L<\/u>, Rocca WA, Mallet A, Agid Y. Mortality in patients with Parkinson’s disease treated by stimulation of the subthalamic nucleus. Mov Disord<\/strong> 2007; 22: 257-261.<\/p>

      Diallo R, Welter ML, Mallet L<\/u>. Therapeutic management of tics in Tourette’s syndrome. Rev Neurol (Paris)<\/strong> 2007; 163: 375-386.<\/p>

      Ardouin C, Voon V, Worbe Y, Abouazar N, Czernecki V, Hosseini H, Pelissolo A, Moro E, Lhommee E, Lang AE, Agid Y, Benabid AL, Pollak P, Mallet L<\/u>, Krack P. Pathological gambling in Parkinson’s disease improves on chronic subthalamic nucleus stimulation. Mov Disord<\/strong> 2006; 21: 1941-1946.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>

      Schupbach M, Gargiulo M, Welter ML, Mallet L<\/u>, Behar C, Houeto JL, Maltete D, Mesnage V, Agid Y. Neurosurgery in Parkinson disease: a distressed mind in a repaired body? Neurology<\/strong> 2006; 66: 1811-1816.<\/p>

      Houeto JL, Mallet L<\/u>, Mesnage V, Tezenas du Montcel S, Behar C, Gargiulo M, Torny F, Pelissolo A, Welter ML, Agid Y. Subthalamic stimulation in Parkinson disease: behavior and social adaptation. Arch Neurol<\/strong> 2006; 63: 1090-1095.<\/p>

      Mallet L<\/u>. [Profound cerebral stimulation: its usefulness for the therapeutic modulation of behavior and emotions]. Encephale<\/strong> 2006; 32: S44-47.<\/p>

      Agid Y, Schupbach M, Gargiulo M, Mallet L<\/u>, Houeto JL, Behar C, Maltete D, Mesnage V, Welter ML. Neurosurgery in Parkinson’s disease: the doctor is happy, the patient less so? J Neural Transm Suppl<\/strong> 2006: 409-414.<\/p>

      Houeto JL, Karachi C, Mallet L<\/u>, Pillon B, Yelnik J, Mesnage V, Welter ML, Navarro S, Pelissolo A, Damier P, Pidoux B, Dormont D, Cornu P, Agid Y. Tourette’s syndrome and deep brain stimulation. J Neurol Neurosurg Psychiatry<\/strong> 2005; 76: 992-995.<\/p>

      Mallet L<\/u>. [Bipolar symptoms, frontal lobe symptoms]. Encephale<\/strong> 2005; 31: S12-15.<\/p>

      Schupbach WM, Chastan N, Welter ML, Houeto JL, Mesnage V, Bonnet AM, Czernecki V, Maltete D, Hartmann A, Mallet L<\/u>, Pidoux B, Dormont D, Navarro S, Cornu P, Mallet A, Agid Y. Stimulation of the subthalamic nucleus in Parkinson’s disease: a 5 year follow up. J Neurol Neurosurg Psychiatry<\/strong> 2005; 76: 1640-1644.\u00a0\u00a0\u00a0\u00a0<\/p>

      Pelissolo A, Mallet L<\/u>, Baleyte JM, Michel G, Cloninger CR, Allilaire JF, Jouvent R. The Temperament and Character Inventory-Revised (TCI-R): psychometric characteristics of the French version. Acta Psychiatr Scand<\/strong> 2005; 112: 126-133.<\/p>

      Houeto JL, Mesnage V, Welter ML, Mallet L<\/u>, Agid Y, Bejjani BP. Subthalamic DBS replaces levodopa in Parkinson’s disease: two-year follow-up. Neurology<\/strong> 2003; 60: 154-155; author reply 154-155.<\/p>

      Mallet L<\/u>, Mesnage V, Houeto JL, Pelissolo A, Yelnik J, Behar C, Gargiulo M, Welter ML, Bonnet AM, Pillon B, Cornu P, Dormont D, Pidoux B, Allilaire JF, Agid Y. Compulsions, Parkinson’s disease, and stimulation. Lancet<\/strong> 2002; 360: 1302-1304.<\/p>

      Houeto JL, Mesnage V, Mallet L<\/u>, Pillon B, Gargiulo M, du Moncel ST, Bonnet AM, Pidoux B, Dormont D, Cornu P, Agid Y. Behavioural disorders, Parkinson’s disease and subthalamic stimulation. J Neurol Neurosurg Psychiatry<\/strong> 2002; 72: 701-707.<\/p>

      Paillere-Martinot M, Caclin A, Artiges E, Poline JB, Joliot M, Mallet L<\/u>, Recasens C, Attar-Levy D, Martinot JL. Cerebral gray and white matter reductions and clinical correlates in patients with early onset schizophrenia. Schizophr Res<\/strong> 2001; 50: 19-26.<\/p>

      Xiberas X, Martinot JL, Mallet L<\/u>, Artiges E, Loc HC, Maziere B, Paillere-Martinot ML. Extrastriatal and striatal D(2) dopamine receptor blockade with haloperidol or new antipsychotic drugs in patients with schizophrenia. Br J Psychiatry<\/strong> 2001; 179: 503-508.<\/p>

      Xiberas X, Martinot JL, Mallet L<\/u>, Artiges E, Canal M, Loc’h C, Maziere B, Paillere-Martinot ML. In vivo extrastriatal and striatal D2 dopamine receptor blockade by amisulpride in schizophrenia. J Clin Psychopharmacol<\/strong> 2001; 21: 207-214.<\/p>

      Falissard B, Corruble E, Mallet L<\/u>, Hardy P. Focused Principal Component Analysis : A promising approach for confirming findings of exploratory analyses ? International Journal of Methods in Psychiatric Research<\/strong> 2001; 10: 191-195.<\/p>

      Doyen C, Mallet L<\/u>, Falissard B, Bouvard MP, Dugas M, Mouren-Simeoni MC. Abnormal psychosocial situations among inpatients from a child and adolescent psychiatric department in a teaching hospital in France. Eur Child Adolesc Psychiatry<\/strong> 1999; 8: 207-213.<\/p>

      Mallet L<\/u>, Mazoyer B, Martinot JL. Functional connectivity in depressive, obsessive-compulsive, and schizophrenic disorders: an explorative correlational analysis of regional cerebral metabolism. Psychiatry Res<\/strong> 1998; 82: 83-93.\u00a0\u00a0\u00a0\u00a0 <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

      Researchgate Orcid Google Luc Mallet MD, PHD, PU-PH, APHP Date and place of birth : 20th January 1967, Paris (XIV) ORCID : 0000-0001-8061-1167 […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page_fullwidth.php","meta":{"footnotes":""},"class_list":["post-519","page","type-page","status-publish","hentry"],"yoast_head":"\nLuc Mallet - NERB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nerb.team\/index.php\/luc-mallet\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Luc Mallet - NERB\" \/>\n<meta property=\"og:description\" content=\"Researchgate Orcid Google Luc Mallet MD, PHD, PU-PH, APHP Date and place of birth : 20th January 1967, Paris (XIV) ORCID : 0000-0001-8061-1167 […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nerb.team\/index.php\/luc-mallet\/\" \/>\n<meta property=\"og:site_name\" content=\"NERB\" \/>\n<meta property=\"article:modified_time\" content=\"2021-08-05T08:38:35+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"19 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/nerb.team\\\/index.php\\\/luc-mallet\\\/\",\"url\":\"https:\\\/\\\/nerb.team\\\/index.php\\\/luc-mallet\\\/\",\"name\":\"Luc Mallet - 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